Because the ova survive and can be fertilized for a week after ovulation, more than one male can sire the same litter.
At the peak of the cycle, females will become estrous, mentally and physically receptive to copulation.
They will experience subsequent estrous cycles semiannually, during which the body prepares for pregnancy.
In domestic dogs, sexual maturity happens around six months to one year for both males and females, although this can be delayed until up to two years of age for some large breeds, and is the time at which female dogs will have their first estrous cycle.
For dogs in England, increased body weight has been found to be negatively correlated with longevity (i.e., the heavier the dog, the shorter its lifespan), and mixed-breed dogs live on average 1.2 years longer than purebred dogs.
The median longevity of mixed-breed dogs, taken as an average of all sizes, is one or more years longer than that of purebred dogs when all breeds are averaged.
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The typical lifespan of dogs varies widely among breeds, but for most, the median longevity (the age at which half the dogs in a population have died and half are still alive) ranges from 10 to 13 years.
Dogs are also vulnerable to some of the same health conditions as humans, including diabetes, dental and heart disease, epilepsy, cancer, hypothyroidism, and arthritis.
